Malignant cell-specific pro-tumorigenic role of type I interferon receptor in breast cancers

Within the microenvironment of solid tumors, stress associated with deficit of nutrients and oxygen as well as tumor-derived factors triggers the phosphorylation-dependent degradation of the IFNAR1 chain of type I interferon (IFN1) receptor and ensuing suppression of the IFN1 pathway. Here we sought...

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Publicat a:Cancer Biol Ther
Autors principals: Odnokoz, Olena, Yu, Pengfei, Peck, Amy R., Sun, Yunguang, Kovatich, Albert J., Hooke, Jeffrey A., Hu, Hai, Mitchell, Edith P., Rui, Hallgeir, Fuchs, Serge Y.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515508/
https://ncbi.nlm.nih.gov/pubmed/32378445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2020.1750297
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