The histone demethylase KDM2B activates FAK and PI3K that control tumor cell motility

Recent studies revealed that the histone demethylase KDM2B regulates the epithelial markers E-Cadherin and ZO-1, the RhoA/B/C-small-GTPases and actin cytoskeleton organization, in DU-145 prostate- and HCT-116 colon-tumor cells. Here we addressed the role of KDM2B in the activation of Focal Adhesion...

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發表在:Cancer Biol Ther
Main Authors: Zacharopoulou, Nefeli, Kallergi, Galatea, Alkahtani, Saad, Tsapara, Anna, Alarifi, Saud, Schmid, Evi, Sukkar, Basma, Kampranis, Sotirios, Lang, Florian, Stournaras, Christos
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2020
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515453/
https://ncbi.nlm.nih.gov/pubmed/32175798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2020.1736481
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