Lost miR-141 and upregulated TM4SF1 expressions associate with poor prognosis of pancreatic cancer: regulation of EMT and angiogenesis by miR-141 and TM4SF1 via AKT

BACKGROUND: Transmembrane-4-L-six-family-1 (TM4SF1) functions to regulate cell growth and mobility and TM4SF1 expression was upregulated in pancreatic cancer. This study further investigated the role of TM4SF1 in regulating pancreatic cancer epithelial-mesenchymal transition (EMT) and angiogenesis a...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Xu, Dong, Yang, Fei, Wu, Kangjian, Xu, Xinxing, Zeng, Kai, An, Yong, Xu, Fubao, Xun, Jiang, Lv, Xiang, Zhang, Xiaohui, Yang, Xiaojun, Xu, Lijian
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515451/
https://ncbi.nlm.nih.gov/pubmed/31906774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2019.1702401
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