Overproduction of the AlgT Sigma Factor Is Lethal to Mucoid Pseudomonas aeruginosa

Pseudomonas aeruginosa isolates from chronic lung infections often overproduce alginate, giving rise to the mucoid phenotype. Isolation of mucoid strains from chronic lung infections correlates with a poor patient outcome. The most common mutation that causes the mucoid phenotype is called mucA22 an...

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Detalles Bibliográficos
Publicado en:J Bacteriol
Main Authors: Cross, Ashley R., Raghuram, Vishnu, Wang, Zihuan, Dey, Debayan, Goldberg, Joanna B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515251/
https://ncbi.nlm.nih.gov/pubmed/32747430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00445-20
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