Bio-activating ultrafine grain titanium: RNA sequencing reveals enhanced mechano-activation of osteoconduction on nanostructured substrates

Titanium is essentially absent from biological systems yet reliably integrates into bone. To achieve osseointegration, titanium must activate biological processes without entering cells, defining it as a bio-activating material. Nanostructuring bulk titanium reduces grain size, increases strength, a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Reiss, Rebecca A., Lowe, Terry C., Sena, Johnny A., Makhnin, Oleg, Connick, Melanie C., Illescas, Patrick E., Davis, Casey F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7514099/
https://ncbi.nlm.nih.gov/pubmed/32970688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237463
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