Prolonged infection triggered by dormant Mycobacterium tuberculosis: Immune and inflammatory responses in lungs of genetically susceptible and resistant mice

We developed an approach for substantial attenuation of Mycobacterium tuberculosis by prolonged culturing under gradually acidifying conditions. Bacteria subjected to acidification lost the capacity to form colonies on solid media, but readily resuscitated their growth in the murine host, providing...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Kondratieva, Tatiana, Shleeva, Margarita, Kapina, Marina, Rubakova, Elvira, Linge, Irina, Dyatlov, Alexander, Kondratieva, Elena, Kaprelyants, Arseny, Apt, Alexander
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7514034/
https://ncbi.nlm.nih.gov/pubmed/32970762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239668
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