Evaluation of the potency of FDA-approved drugs on wild type and mutant SARS-CoV-2 helicase (Nsp13)

SARS-CoV-2 has caused COVID-19 outbreak with nearly 2 M infected people and over 100K death worldwide, until middle of April 2020. There is no confirmed drug for the treatment of COVID-19 yet. As the disease spread fast and threaten human life, repositioning of FDA approved drugs may provide fast op...

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Vydáno v:Int J Biol Macromol
Hlavní autoři: Ugurel, Osman Mutluhan, Mutlu, Ozal, Sariyer, Emrah, Kocer, Sinem, Ugurel, Erennur, Inci, Tugba Gul, Ata, Oguz, Turgut-Balik, Dilek
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier B.V. 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513821/
https://ncbi.nlm.nih.gov/pubmed/32980406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijbiomac.2020.09.138
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