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Mechanism and implications of morphogen shuttling: lessons learned from Dorsal and Cactus in Drosophila

In a developing animal, morphogen gradients act to pattern tissues into distinct domains of cell types. However, despite their prevalence in development, morphogen gradient formation is a matter of debate. In our recent publication, we showed that the Dorsal/NF-κB morphogen gradient, which patterns...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Dev Biol
Hauptverfasser: Schloop, Allison E., Carrell-Noel, Sophia, Friedman, Jeramey, Thomas, Alexander, Reeves, Gregory T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513736/
https://ncbi.nlm.nih.gov/pubmed/31987808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2020.01.011
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