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Using collections of structural models to predict changes of binding affinity caused by mutations in protein–protein interactions

Protein–protein interactions (PPIs) in all the molecular aspects that take place both inside and outside cells. However, determining experimentally the structure and affinity of PPIs is expensive and time consuming. Therefore, the development of computational tools, as a complement to experimental m...

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Publicat a:Protein Sci
Autors principals: Meseguer, Alberto, Dominguez, Lluis, Bota, Patricia M., Aguirre‐Plans, Joaquim, Bonet, Jaume, Fernandez‐Fuentes, Narcis, Oliva, Baldo
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513729/
https://ncbi.nlm.nih.gov/pubmed/32797645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3930
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