LncRNA MALAT1 facilitates inflammasome activation via epigenetic suppression of Nrf2 in Parkinson’s disease

The goal of the present study was to elucidate the mechanism by which long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (lncRNA MALAT1) promotes inflammation in Parkinson’s disease (PD). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) was used to induce PD development in...

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Bibliografiske detaljer
Udgivet i:Mol Brain
Main Authors: Cai, Li-Jun, Tu, Li, Huang, Xiao-Mo, Huang, Jia, Qiu, Nan, Xie, Guang-Hong, Liao, Jian-Xiong, Du, Wei, Zhang, Ying-Yue, Tian, Jin-Yong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513532/
https://ncbi.nlm.nih.gov/pubmed/32972446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00656-8
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