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A modified protocol of Capture-C allows affordable and flexible high-resolution promoter interactome analysis

Large-scale epigenomic projects have mapped hundreds of thousands of potential regulatory sites in the human genome, but only a small proportion of these elements are proximal to transcription start sites. It is believed that the majority of these sequences are remote promoter-activating genomic sit...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Golov, Arkadiy K., Abashkin, Dmitrii A., Kondratyev, Nikolay V., Razin, Sergey V., Gavrilov, Alexey A., Golimbet, Vera E.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511934/
https://ncbi.nlm.nih.gov/pubmed/32968144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72496-4
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