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Combining 3D modeling with artificial intelligence to increase specificity and precision in peptide:MHC binding predictions

The reliable prediction of the affinity of candidate peptides for the major histocompatibility complex (MHC) is important for predicting their potential antigenicity, and thus influences medical applications, such as decisions on their inclusion in T cell-based vaccines. Here, we present a rapid, pr...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Aranha, Michelle P., Jewel, Yead S. M., Beckman, Robert A., Weiner, Louis M., Mitchell, Julie C., Parks, Jerry M., Smith, Jeremy C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511449/
https://ncbi.nlm.nih.gov/pubmed/32878910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900918
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