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Detecting protein-protein interactions by Xe-129 NMR

Detection of protein-protein interactions (PPIs) is limited by current bioanalytical methods. A protein complementation assay (PCA), split TEM-1 β-lactamase, interacts with xenon at the interface of the TEM-1 fragments. Reconstitution of TEM-1—promoted here by cFos/cJun leucine zipper interaction—gi...

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Publicado en:Chem Commun (Camb)
Main Authors: Zhao, Zhuangyu, Roose, Benjamin W., Zemerov, Serge D., Stringer, Madison A., Dmochowski, Ivan J.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511426/
https://ncbi.nlm.nih.gov/pubmed/32814938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cc02988b
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