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REM sleep promotes experience-dependent dendritic spine elimination in the mouse cortex

In many parts of the nervous system, experience-dependent refinement of neuronal circuits predominantly involves synapse elimination. The role of sleep in this process remains unknown. We investigated the role of sleep in experience-dependent dendritic spine elimination of layer 5 pyramidal neurons...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Zhou, Yanmei, Lai, Cora Sau Wan, Bai, Yang, Li, Wei, Zhao, Ruohe, Yang, Guang, Frank, Marcos G., Gan, Wen-Biao
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511313/
https://ncbi.nlm.nih.gov/pubmed/32968048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18592-5
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