Visualization of the distribution of nanoparticle-formulated AZD2811 in mouse tumor model using matrix-assisted laser desorption ionization mass spectrometry imaging

Penetration of nanoparticles into viable tumor regions is essential for an effective response. Mass spectrometry imaging (MSI) is a novel method for evaluating the intratumoral pharmacokinetics (PK) of a drug in terms of spatial distribution. The application of MSI for analysis of nanomedicine PK re...

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Vydáno v:Sci Rep
Hlavní autoři: Ryu, Shoraku, Ohuchi, Mayu, Yagishita, Shigehiro, Shimoi, Tatsunori, Yonemori, Kan, Tamura, Kenji, Fujiwara, Yasuhiro, Hamada, Akinobu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511311/
https://ncbi.nlm.nih.gov/pubmed/32968211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72665-5
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