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Safety, Tolerability and Pharmacokinetics of Vidofludimus calcium (IMU-838) After Single and Multiple Ascending Oral Doses in Healthy Male Subjects

BACKGROUND AND OBJECTIVE: Vidofludimus is a potent and selective inhibitor of human mitochondrial enzyme dihydroorotate dehydrogenase (DHODH). The clinical efficacy and safety profile of vidofludimus has been analyzed in patients suffering from rheumatoid arthritis and Crohn’s disease and ulcerative...

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Detalhes bibliográficos
Publicado no:Eur J Drug Metab Pharmacokinet
Main Authors: Muehler, Andreas, Kohlhof, Hella, Groeppel, Manfred, Vitt, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511286/
https://ncbi.nlm.nih.gov/pubmed/32361977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-020-00623-7
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