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Pharmacokinetic and Pharmacodynamic Studies of Elacestrant, A Novel Oral Selective Estrogen Receptor Degrader, in Healthy Post-Menopausal Women

BACKGROUND AND OBJECTIVES: Advanced estrogen receptor-positive (ER+) breast cancer is currently treated with endocrine therapy. Elacestrant is a novel, nonsteroidal, selective estrogen receptor degrader with complex dose-related ER agonist/antagonist activity that is being developed as a treatment o...

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Detalhes bibliográficos
Publicado no:Eur J Drug Metab Pharmacokinet
Main Authors: Conlan, Maureen G., de Vries, Erik F. J., Glaudemans, AWJM, Wang, Yamei, Troy, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511284/
https://ncbi.nlm.nih.gov/pubmed/32661909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-020-00635-3
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