Characterization of Resident Corneal Plasmacytoid Dendritic Cells and Their Pivotal Role in Herpes Simplex Keratitis

The presence and potential functions of resident plasmacytoid dendritic cells (pDCs) in peripheral tissues is unclear. We report that pDCs constitutively populate naïve corneas and are increased during sterile injuries or acute herpes simplex virus 1 (HSV-1) keratitis. Their local depletion leads to...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Jamali, Arsia, Hu, Kai, Sendra, Victor G., Blanco, Tomas, Lopez, Maria J., Ortiz, Gustavo, Qazi, Yureeda, Zheng, Lixin, Turhan, Aslihan, Harris, Deshea L., Hamrah, Pedram
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511260/
https://ncbi.nlm.nih.gov/pubmed/32877681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108099
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