Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex

The pathogenesis of Helicobacter pylori-associated gastric cancer is dependent on delivery of CagA into host cells through a type IV secretion system (T4SS). The H. pylori Cag T4SS includes a large membrane-spanning core complex containing five proteins, organized into an outer membrane cap (OMC), a...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Sheedlo, Michael J, Chung, Jeong Min, Sawhney, Neha, Durie, Clarissa L, Cover, Timothy L, Ohi, Melanie D, Lacy, D Borden
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Microbiology and Infectious Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511236/
https://ncbi.nlm.nih.gov/pubmed/32876048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59495
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