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Stoichiometric interactions explain spindle dynamics and scaling across 100 million years of nematode evolution

The spindle shows remarkable diversity, and changes in an integrated fashion, as cells vary over evolution. Here, we provide a mechanistic explanation for variations in the first mitotic spindle in nematodes. We used a combination of quantitative genetics and biophysics to rule out broad classes of...

詳細記述

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書誌詳細
出版年:eLife
主要な著者: Farhadifar, Reza, Yu, Che-Hang, Fabig, Gunar, Wu, Hai-Yin, Stein, David B, Rockman, Matthew, Müller-Reichert, Thomas, Shelley, Michael J, Needleman, Daniel J
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511230/
https://ncbi.nlm.nih.gov/pubmed/32966209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55877
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