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The effect of size, charge, and peptide ligand length on kidney targeting by small, organic nanoparticles

Chronic kidney disease (CKD) affects 15% of the US adult population. However, most clinically available drugs for CKD show low bioavailability to the kidneys and non‐specific uptake by other organs which results in adverse side effects. Hence, a targeted, drug delivery strategy to enhance kidney dru...

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Bibliografiske detaljer
Udgivet i:Bioeng Transl Med
Main Authors: Huang, Yi, Jiang, Kairui, Zhang, Xuting, Chung, Eun Ji
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510478/
https://ncbi.nlm.nih.gov/pubmed/33005739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10173
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