Pushing beyond specifications: Evaluation of linearity and clinical performance of the cobas 6800/8800 SARS-CoV-2 RT-PCR assay for reliable quantification in blood and other materials outside recommendations

BACKGROUND: The ongoing SARS-CoV-2 pandemic presents a unique challenge to diagnostic laboratories. There are preliminary studies correlating qRT-PCR results from different materials to clinical outcomes, yet, comparability is limited due to the plethora of different assays used for diagnostics. In...

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Vydáno v:J Clin Virol
Hlavní autoři: Nörz, Dominik, Frontzek, André, Eigner, Ulrich, Oestereich, Lisa, Wichmann, Dominic, Kluge, Stefan, Fischer, Nicole, Aepfelbacher, Martin, Pfefferle, Susanne, Lütgehetmann, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier B.V. 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510425/
https://ncbi.nlm.nih.gov/pubmed/33011643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcv.2020.104650
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