Amifostine protects from the peripheral sensory neuropathy induced by oxaliplatin in mice

Sensory neuropathy is a dose-limiting side effect of oxaliplatin-based cancer treatment. This study investigated the antinociceptive effect of amifostine and its potential neuroprotective mechanisms on the oxaliplatin-related peripheral sensory neuropathy in mice. Oxaliplatin (1 mg/kg) was injected...

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Publicado en:Braz J Med Biol Res
Autores principales: Pereira, A.F., Lino, J.A., Alves, B.W.F., Lisboa, M.R.P., Pontes, R.B., Leite, C.A.V.G., Nogueira, R.B., Lima-Júnior, R.C.P., Vale, M.L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Associação Brasileira de Divulgação Científica 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510240/
https://ncbi.nlm.nih.gov/pubmed/32965323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X202010263
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