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Structural Analysis of Cj1427, an Essential NAD-dependent Dehydrogenase for the Biosynthesis of the Heptose Residues in the Capsular Polysaccharides of Campylobacter jejuni

Many strains of Campylobacter jejuni display modified heptose residues in their capsular polysaccharides (CPS). The precursor heptose was previously shown to be GDP-d-glycero-α-D-manno-heptose, from which a variety of modifications to the sugar moiety have been observed. These modifications include...

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Publicado en:Biochemistry
Main Authors: Huddleston, Jamison P., Anderson, Thomas K., Spencer, Keelan D., Thoden, James B., Raushel, Frank M., Holden, Hazel M.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509852/
https://ncbi.nlm.nih.gov/pubmed/32168450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00096
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