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Recent Advances in the Understanding of the Reaction Chemistries of the Heme Catabolizing Enzymes HO and BVR Based on High Resolution Protein Structures

In mammals, catabolism of the heme group is indispensable for life. Heme is first cleaved by the enzyme Heme Oxygenase (HO) to the linear tetrapyrrole Biliverdin IXα (BV), and BV is then converted into bilirubin by Biliverdin Reductase (BVR). HO utilizes three Oxygen molecules (O2) and seven electro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Curr Med Chem
Egile Nagusiak: Sugishima, Masakazu, Wada, Kei, Fukuyama, Keiichi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Bentham Science Publishers 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509768/
https://ncbi.nlm.nih.gov/pubmed/30556496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/0929867326666181217142715
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