Stiffness of HIV‐1 Mimicking Polymer Nanoparticles Modulates Ganglioside‐Mediated Cellular Uptake and Trafficking

The monosialodihexosylganglioside, GM3, and its binding to CD169 (Siglec‐1) have been indicated as key factors in the glycoprotein‐independent sequestration of the human immunodeficiency virus‐1 (HIV‐1) in virus‐containing compartments (VCCs) in myeloid cells. Here, lipid‐wrapped polymer nanoparticl...

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Опубликовано в: :Adv Sci (Weinh)
Главные авторы: Eshaghi, Behnaz, Alsharif, Nourin, An, Xingda, Akiyama, Hisashi, Brown, Keith A., Gummuluru, Suryaram, Reinhard, Björn M.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
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Full Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509657/
https://ncbi.nlm.nih.gov/pubmed/32999830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202000649
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