Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results from a randomised, placebo-controlled trial

OBJECTIVES: This ongoing Phase-2, randomised, placebo-controlled, double-blind study evaluated the efficacy, safety and pharmacokinetics of intravenous belimumab in childhood-onset systemic lupus erythematosus (cSLE). METHODS: Patients (5 to 17 years) were randomised to belimumab 10 mg/kg intravenou...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Brunner, Hermine I, Abud-Mendoza, Carlos, Viola, Diego O, Calvo Penades, Inmaculada, Levy, Deborah, Anton, Jordi, Calderon, Julia E, Chasnyk, Vyacheslav G, Ferrandiz, Manuel A, Keltsev, Vladimir, Paz Gastanaga, Maria E, Shishov, Michael, Boteanu, Alina Lucica, Henrickson, Michael, Bass, Damon, Clark, Kenneth, Hammer, Anne, Ji, Beulah N, Nino, Antonio, Roth, David A, Struemper, Herbert, Wang, Mei-Lun, Martini, Alberto, Lovell, Daniel, Ruperto, Nicolino
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Systemic Lupus Erythematosus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509523/
https://ncbi.nlm.nih.gov/pubmed/32699034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2020-217101
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