Gut Dysbiosis and Increased Intestinal Permeability Drive microRNAs, NLRP-3 Inflammasome and Liver Fibrosis in a Nutritional Model of Non-Alcoholic Steatohepatitis in Adult Male Sprague Dawley Rats

BACKGROUND/AIM: The interactions between the gut and liver have been described in the progression of non-alcoholic steatohepatitis (NASH). The aim of this study was to develop an experimental nutritional model of NASH simulating metabolic changes occurring in humans. MATERIALS AND METHODS: Adult mal...

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Detalhes bibliográficos
Publicado no:Clin Exp Gastroenterol
Main Authors: Longo, Larisse, Tonin Ferrari, Jéssica, Rampelotto, Pabulo Henrique, Hirata Dellavia, Gustavo, Pasqualotto, Amanda, P Oliveira, Claudia, Thadeu Schmidt Cerski, Carlos, Reverbel da Silveira, Themis, Uribe-Cruz, Carolina, Álvares-da-Silva, Mário Reis
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509481/
https://ncbi.nlm.nih.gov/pubmed/32982365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEG.S262879
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