Macrophage-derived exosomes attenuate fibrosis in airway epithelial cells through delivery of antifibrotic miR-142-3p

INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease of unknown aetiology and cure. Recent studies have reported a dysregulation of exosomal microRNAs (miRs) in the IPF context. However, the impact of IPF-related exosomal miRs on the progression of p...

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Detalles Bibliográficos
Publicado en:Thorax
Main Authors: Guiot, Julien, Cambier, Maureen, Boeckx, Amandine, Henket, Monique, Nivelles, Olivier, Gester, Fanny, Louis, Edouard, Malaise, Michel, Dequiedt, Franck, Louis, Renaud, Struman, Ingrid, Njock, Makon-Sébastien
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2020
Assuntos:
Interstitial Lung Disease
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509395/
https://ncbi.nlm.nih.gov/pubmed/32759383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2019-214077
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