Mechanism underlying increased cardiac extracellular matrix deposition in perinatal nicotine-exposed offspring

Although increased predisposition to cardiac fibrosis and cardiac dysfunction has been demonstrated in the perinatally nicotine-exposed heart, the underlying mechanisms remain unclear. With the use of a well-established rat model and cultured primary neonatal rat cardiac fibroblasts, the effect of p...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Chuang, Tsai-Der, Ansari, Aamir, Yu, Celia, Sakurai, Reiko, Harb, Amir, Liu, Jie, Khorram, Omid, Rehan, Virender K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509277/
https://ncbi.nlm.nih.gov/pubmed/32795172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00021.2020
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