Divergent Transcription of the Nkx2-5 Locus Generates Two Enhancer RNAs with Opposing Functions

Enhancer RNAs (eRNAs) are a subset of long noncoding RNA generated from genomic enhancers: they are thought to act as potent promoters of the expression of nearby genes through interaction with the transcriptional and epigenomic machineries. In the present work, we describe two eRNAs transcribed fro...

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Veröffentlicht in:iScience
Hauptverfasser: Salamon, Irene, Serio, Simone, Bianco, Simona, Pagiatakis, Christina, Crasto, Silvia, Chiariello, Andrea M., Conte, Mattia, Cattaneo, Paola, Fiorillo, Luca, Felicetta, Arianna, di Pasquale, Elisa, Kunderfranco, Paolo, Nicodemi, Mario, Papait, Roberto, Condorelli, Gianluigi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509214/
https://ncbi.nlm.nih.gov/pubmed/33083767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101539
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