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Organoarsenicals inhibit bacterial peptidoglycan biosynthesis by targeting the essential enzyme MurA

Trivalent organoarsenicals such as methylarsenite (MAs(III)) are considerably more toxic than inorganic arsenate (As(V)) or arsenite (As(III)). In microbial communities MAs(III) exhibits significant antimicrobial activity. Although MAs(III) and other organoarsenicals contribute to the global arsenic...

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Publicado en:Chemosphere
Autores principales: Garbinski, Luis D., Rosen, Barry P., Yoshinaga, Masafumi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509207/
https://ncbi.nlm.nih.gov/pubmed/32957300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemosphere.2020.126911
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