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Spinal cord atrophy in a primary progressive multiple sclerosis trial: Improved sample size using GBSI
BACKGROUND: We aimed to evaluate the implications for clinical trial design of the generalised boundary-shift integral (GBSI) for spinal cord atrophy measurement. METHODS: We included 220 primary-progressive multiple sclerosis patients from a phase 2 clinical trial, with baseline and week-48 3DT1-we...
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| Publicado no: | Neuroimage Clin |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7509079/ https://ncbi.nlm.nih.gov/pubmed/32961403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2020.102418 |
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