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Insights into the biased activity of dextromethorphan and haloperidol towards SARS-CoV-2 NSP6: in silico binding mechanistic analysis

ABSTRACT: The outbreak of novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus continually led to infect a large population worldwide. SARS-CoV-2 utilizes its NSP6 and Orf9c proteins to interact with sigma receptors that are implicate...

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Bibliografski detalji
Izdano u:J Mol Med (Berl)
Glavni autori: Pandey, Preeti, Prasad, Kartikay, Prakash, Amresh, Kumar, Vijay
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509052/
https://ncbi.nlm.nih.gov/pubmed/32965508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01980-1
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