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Sarcoma stratification by combined pH2AX and MAP17 (PDZK1IP1) levels for a better outcome on doxorubicin plus olaparib treatment

Sarcomas constitute a rare heterogeneous group of tumors, including a wide variety of histological subtypes. Despite advances in our understanding of the pathophysiology of the disease, first-line sarcoma treatment options are still limited and new treatment approaches are needed. Histone H2AX phosp...

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Podrobná bibliografie
Vydáno v:Signal Transduct Target Ther
Hlavní autoři: Perez, Marco, García-Heredia, José Manuel, Felipe-Abrio, Blanca, Muñoz-Galván, Sandra, Martín-Broto, Javier, Carnero, Amancio
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508862/
https://ncbi.nlm.nih.gov/pubmed/32963243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-00246-z
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