Dry powder aerosol containing muco-inert particles for excipient enhanced growth pulmonary drug delivery

Tenacious sputum poses a critical diffusion barrier for aerosol antibiotics used to treat cystic fibrosis (CF) lung infection. We conducted a proof-of-concept study using dense poly(ethylene glycol) coated polystyrene nanoparticles (PS-PEG NPs) as model muco-inert particles (MIP) formulated as a pow...

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Bibliografiset tiedot
Julkaisussa:Nanomedicine
Päätekijät: Chai, Guihong, Hassan, Amr, Meng, Tuo, Lou, Lihua, Ma, Jonathan, Simmers, Russell, Zhou, Lei, MEngr, Bruce K. Rubin, Zhou, Qi (Tony), Longest, P. Worth, Hindle, Michael, Xu, Qingguo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508849/
https://ncbi.nlm.nih.gov/pubmed/32623017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2020.102262
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