Population Pharmacokinetic Study of Ceftriaxone in Elderly Patients, Using Cystatin C-Based Estimates of Renal Function To Account for Frailty

Ceftriaxone is widely used for respiratory and urinary infections in elderly and frail patients, but there are few pharmacokinetic studies. A prospective population pharmacokinetic study of ceftriaxone in adults over 65 years old was undertaken. Dried blood spots collected at baseline (predose) and...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Tan, Shu Jin, Cockcroft, Matthew, Page-Sharp, Madhu, Arendts, Glenn, Davis, Timothy M. E., Moore, Brioni R., Batty, Kevin T., Salman, Sam, Manning, Laurens
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508575/
https://ncbi.nlm.nih.gov/pubmed/32778543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00874-20
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