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Risk of Nonunion with Nonselective NSAIDs, COX-2 Inhibitors, and Opioids

BACKGROUND: Cyclooxygenase-2 (COX-2) has been found to be important for fracture-healing in animal models, raising concerns about use of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors after fractures. We evaluated associations of NSAIDs, COX-2 inhibitors, and opioids wi...

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Détails bibliographiques
Publié dans:J Bone Joint Surg Am
Auteurs principaux: George, Michael D., Baker, Joshua F., Leonard, Charles E., Mehta, Samir, Miano, Todd A., Hennessy, Sean
Format: Artigo
Langue:Inglês
Publié: Journal of Bone and Joint Surgery, Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508275/
https://ncbi.nlm.nih.gov/pubmed/32675672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.19.01415
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