Pharmacological Inhibition of Galectin-3 Ameliorates Diabetes-Associated Cognitive Impairment, Oxidative Stress and Neuroinflammation in vivo and in vitro

BACKGROUND: In diabetes, cognitive impairment is linked with oxidative stress and neuroinflammation. As the only chimeric member of the galectin family, galectin-3 (Gal3) induces neuroinflammation and cognitive impairment in models of Alzheimer’s disease (AD); however, its role in diabetes-associate...

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Bibliografiske detaljer
Udgivet i:J Inflamm Res
Main Authors: Yin, Qingqing, Chen, Jian, Ma, Shizhan, Dong, Chuanfang, Zhang, Yue, Hou, Xunyao, Li, Shangbin, Liu, Bin
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508034/
https://ncbi.nlm.nih.gov/pubmed/32982368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S273858
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