Poly-IC enhances the effectiveness of cancer immunotherapy by promoting T cell tumor infiltration

BACKGROUND: Immunotherapies, such as immune checkpoint inhibitors and adoptive cell therapies, have revolutionized cancer treatment and resulted in complete and durable responses in some patients. Unfortunately, most immunotherapy treated patients still fail to respond. Absence of T cell infiltratio...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Sultan, Hussein, Wu, Juan, Fesenkova, Valentyna I, Fan, Aaron E, Addis, Diane, Salazar, Andres M, Celis, Esteban
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2020
Témata:
Clinical/Translational Cancer Immunotherapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507896/
https://ncbi.nlm.nih.gov/pubmed/32958686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001224
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