Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma

OBJECTIVES: To explore lymphocyte infiltration as a potential mechanism behind CXCL14-mediated tumor growth suppression in oral cavity squamous cell carcinoma (OSCC). METHODS: We analyzed single cell RNA-sequencing (scRNA-seq) data from OSCC to identify expression changes among malignant cells in ly...

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Foilsithe in:J Immunother Cancer
Main Authors: Parikh, Anuraag, Shin, JuneHo, Faquin, William, Lin, Derrick T, Tirosh, Itay, Sunwoo, John B, Puram, Sidharth V
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMJ Publishing Group 2020
Ábhair:
Basic Tumor Immunology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507891/
https://ncbi.nlm.nih.gov/pubmed/32958684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001048
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