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Nanodisc scaffold peptide (NSP(r)) replaces detergent by reconstituting acyl-CoA:cholesterol acyltransferase 1 into peptidiscs
To conduct biochemical studies in vitro, membrane proteins (MPs) must be solubilized with detergents. While detergents are great tools, they can also inhibit the biological activity and/or perturb oligomerization of individual MPs. Nanodisc scaffold peptide (NSP(r)), an amphipathic peptide analog of...
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| Publicado no: | Arch Biochem Biophys |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7507747/ https://ncbi.nlm.nih.gov/pubmed/32735863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2020.108518 |
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