Effect of Ketamine on Limbic GABA and Glutamate: A Human In Vivo Multivoxel Magnetic Resonance Spectroscopy Study

INTRODUCTION: Converging evidence suggests that ketamine elicits antidepressant effects via enhanced neuroplasticity precipitated by a surge of glutamate and modulation of GABA. Magnetic resonance spectroscopic imaging (MRSI) illustrates changes to cerebral glutamate and GABA immediately following k...

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Pubblicato in:Front Psychiatry
Autori principali: Silberbauer, Leo R., Spurny, Benjamin, Handschuh, Patricia, Klöbl, Manfred, Bednarik, Petr, Reiter, Birgit, Ritter, Vera, Trost, Patricia, Konadu, Melisande E., Windpassinger, Marita, Stimpfl, Thomas, Bogner, Wolfgang, Lanzenberger, Rupert, Spies, Marie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Psychiatry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507577/
https://ncbi.nlm.nih.gov/pubmed/33101078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2020.549903
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