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The NRF2 stimulating agent, tin protoporphyrin, activates protective cytokine pathways in healthy human subjects and in patients with chronic kidney disease
BACKGROUND: Tin protoporphyrin (SnPP), a heme oxygenase 1 (HO‐1) inhibitor, triggers adaptive tissue responses that confer potent protection against acute renal‐ and extra‐renal tissue injuries. This effect is mediated, in part, via SnPP‐induced activation of the cytoprotective Nrf2 pathway. However...
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| Publicado en: | Physiol Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7507518/ https://ncbi.nlm.nih.gov/pubmed/32940965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14566 |
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