Internal Ribosome Entry Sites Mediate Cap-Independent Translation of Bmi1 in Nasopharyngeal Carcinoma

Bmi1 is overexpressed in multiple human cancers. We previously reported the oncogenic function and the transcription regulation mechanisms of Bmi1 in nasopharyngeal carcinoma (NPC). In this study, we observed that the mRNA and the protein levels of Bmi1 were strictly inconsistent in NPC cell lines a...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Wang, Hongbo, Zhu, Yunjia, Hu, Lijuan, Li, Yangyang, Liu, Guihong, Xia, Tianliang, Xiong, Dan, Luo, Yiling, Liu, Binliu, An, Yu, Li, Manzhi, Huang, Yuehua, Zhong, Qian, Zeng, Musheng
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7506037/
https://ncbi.nlm.nih.gov/pubmed/33014838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01678
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