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Semaphorin 4D Induces an Imbalance of Th17/Treg Cells by Activating the Aryl Hydrocarbon Receptor in Ankylosing Spondylitis

OBJECTIVES: Semaphorin 4D (Sema4D) is constitutively expressed on T cells and osteoclasts, and regulates T cell proliferation and bone remodeling. In addition, several studies have shown that Sema4D is involved in the pathogenesis of autoimmunity. We undertook this study to investigate the mechanism...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Xie, Jianmin, Wang, Zitao, Wang, Wen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7505929/
https://ncbi.nlm.nih.gov/pubmed/33013906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02151
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