Cadherin clusters stabilized by a combination of specific and nonspecific cis-interactions

We demonstrate a combined experimental and computational approach for the quantitative characterization of lateral interactions between membrane-associated proteins. In particular, weak, lateral (cis) interactions between E-cadherin extracellular domains tethered to supported lipid bilayers, were st...

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Bibliographic Details
Published in:eLife
Main Authors: Thompson, Connor J, Su, Zhaoqian, Vu, Vinh H, Wu, Yinghao, Leckband, Deborah E, Schwartz, Daniel K
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2020
Subjects:
Structural Biology and Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7505656/
https://ncbi.nlm.nih.gov/pubmed/32876051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59035
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