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Combination of Cordycepin and Apatinib Synergistically Inhibits NSCLC Cells by Down-Regulating VEGF/PI3K/Akt Signaling Pathway

BACKGROUND: The application of apatinib is immensely limited by its acquired drug resistance. This research investigates whether cordycepin, a component from Cordyceps could synergize with apatinib to improve its anticancer effect on non-small cell lung cancer (NSCLC) cells. METHODS: The NSCLC cell...

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Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Liao, Xiaozhong, Tao, Lanting, Guo, Wei, Wu, Zhuo-Xun, Du, Haiyan, Wang, Jing, Zhang, Jue, Chen, Hanrui, Chen, Zhe-Sheng, Lin, Lizhu, Sun, Lingling
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7505117/
https://ncbi.nlm.nih.gov/pubmed/33014856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01732
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