Intratumoral Distribution of Lactate and the Monocarboxylate Transporters 1 and 4 in Human Glioblastoma Multiforme and Their Relationships to Tumor Progression-Associated Markers

(1) Background: Metabolic reprogramming has been postulated to be one of the hallmarks of cancer, thus representing a promising therapeutic target also in glioblastoma multiforme (GBM). Hypoxic tumor cells produce lactate, and monocarboxylate transporters (MCTs) play an important role in its distrib...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Kubelt, Carolin, Peters, Sönke, Ahmeti, Hajrullah, Huhndorf, Monika, Huber, Lukas, Cohrs, Gesa, Hövener, Jan-Bernd, Jansen, Olav, Synowitz, Michael, Held-Feindt, Janka
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504270/
https://ncbi.nlm.nih.gov/pubmed/32872409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176254
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