Inhibition of Butyrylcholinesterase and Human Monoamine Oxidase-B by the Coumarin Glycyrol and Liquiritigenin Isolated from Glycyrrhiza uralensis

Eight compounds were isolated from the roots of Glycyrrhiza uralensis and tested for cholinesterase (ChE) and monoamine oxidase (MAO) inhibitory activities. The coumarin glycyrol (GC) effectively inhibited butyrylcholinesterase (BChE) and acetylcholinesterase (AChE) with IC(50) values of 7.22 and 14...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Jeong, Geum Seok, Kang, Myung-Gyun, Lee, Joon Yeop, Lee, Sang Ryong, Park, Daeui, Cho, MyoungLae, Kim, Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504216/
https://ncbi.nlm.nih.gov/pubmed/32859055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25173896
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